Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7
USERS' SCORE
Good
Based on 3 Reviews
8.3
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%**
Polyunsaturated Fat
1 g
***
Evening Primrose Oil
1,000 mg (1 g)
***
Cis-Linoleic Acid (LA)
730 mg
***
Gamma-Linolenic Acid (GLA)
90 mg
***
Top Medical Research Studies
7
We examined the latest insights into herbal therapies for rheumatoid arthritis, including evening primrose oil. Our analysis included 22 studies, revealing moderate evidence suggesting that gamma linolenic acid (GLA), found in evening primrose oil, may ease pain and disability related to RA.
However, while some benefits were noted, the evidence remains mixed and the risk of side effects should not be overlooked. More comprehensive studies are needed to firmly establish its effectiveness for RA treatment.
However, while some benefits were noted, the evidence remains mixed and the risk of side effects should not be overlooked. More comprehensive studies are needed to firmly establish its effectiveness for RA treatment.
Read More
7
Evening primrose oil shows symptom relief
We explored the impact of evening primrose oil (EPO) on rheumatoid arthritis (RA) in a double-blind, placebo-controlled study involving 49 patients. Participants took EPO or EPO combined with fish oil, with the aim of reducing reliance on non-steroidal anti-inflammatory drugs (NSAIDs).
After 12 months, those on EPO noted significant improvements and were able to cut back on their NSAIDs. However, once they switched to placebo, they relapsed, revealing that while EPO may improve symptoms, it doesn't change the underlying disease. Thus, it appears evening primrose oil can help manage RA symptoms and lessen NSAID use, but it doesn’t modify the disease itself.
After 12 months, those on EPO noted significant improvements and were able to cut back on their NSAIDs. However, once they switched to placebo, they relapsed, revealing that while EPO may improve symptoms, it doesn't change the underlying disease. Thus, it appears evening primrose oil can help manage RA symptoms and lessen NSAID use, but it doesn’t modify the disease itself.
Read More
4
We looked into how evening primrose oil might help relieve symptoms of rheumatoid arthritis in a study involving 40 patients over six months. Patients were split into two groups: one received evening primrose oil, while the other got a placebo.
While there were mild improvements in morning stiffness for those taking evening primrose oil, olive oil actually showed a more significant reduction in pain over time. Therefore, evening primrose oil may offer some benefits, but olive oil revealed notable advantages that shouldn't be overlooked.
While there were mild improvements in morning stiffness for those taking evening primrose oil, olive oil actually showed a more significant reduction in pain over time. Therefore, evening primrose oil may offer some benefits, but olive oil revealed notable advantages that shouldn't be overlooked.
Read More
Most Useful Reviews
7.5
Boosts immunity
I combine evening primrose oil with B vitamins to enhance immunity for managing rheumatoid arthritis. This oil also improves skin turgor and benefits the overall condition of hair and nails. Regular use provides antimicrobial, regenerating, and anti-inflammatory effects.
Read More
7.5
Aids joint inflammation
Evening primrose oil aids in hormone restoration and has positive effects on women's health. While there’s no specific information regarding cholesterol, it does help regulate blood pressure. Importantly, it assists in treating rheumatoid arthritis. The oil is rich in omega-6 fatty polyunsaturated fatty acids, and a single small package lasts for a month of use.
Read More
7.5
Effective for acne
I have continuously taken evening primrose oil for several years, considering it the best female supplement for my skin. It has significantly helped with acne and has provided additional benefits, such as alleviating PMS pain and strengthening my nails. Most notably, it has proven benefits for rheumatoid arthritis and supports youthful skin.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7
- All Researches
8
We examined how supplementation with marine omega-3 fatty acids and evening primrose oil (rich in GLA) could help relieve rheumatoid arthritis symptoms in a randomized trial of 60 patients.
After 12 weeks, those taking either fish oil alone or in combination with evening primrose oil showed remarkable improvements in joint pain and disease activity compared to those who received no supplements.
This suggests that these oils may significantly benefit people dealing with the inflammation and discomfort of rheumatoid arthritis.
After 12 weeks, those taking either fish oil alone or in combination with evening primrose oil showed remarkable improvements in joint pain and disease activity compared to those who received no supplements.
This suggests that these oils may significantly benefit people dealing with the inflammation and discomfort of rheumatoid arthritis.
Read More
8
EPO shows promise for arthritis
We investigated the potential benefits of evening primrose oil (EPO) on rheumatoid arthritis, focusing on its anti-inflammatory and anti-oxidant properties. Using an animal model, we found that EPO normalized body weight and reduced inflammatory markers in rats with arthritis.
Moreover, it showed improvement in joint health and decreased inflammation when used alone or alongside traditional pain relievers like aspirin and celecoxib. While these findings are promising, it’s essential to note that the impact is still being explored in more extensive studies.
Moreover, it showed improvement in joint health and decreased inflammation when used alone or alongside traditional pain relievers like aspirin and celecoxib. While these findings are promising, it’s essential to note that the impact is still being explored in more extensive studies.
Read More
8
Evening primrose oil reduces inflammation
We explored the effects of evening primrose oil and its key components, long-chain fatty alcohols (LCFAs), on inflammation. In our tests, these compounds demonstrated a remarkable ability to reduce inflammatory responses in lab-based mouse macrophages, decreasing the production of factors that drive inflammation.
While evening primrose oil has traditionally been used for conditions like rheumatoid arthritis, the study highlighted that these LCFAs specifically target gene expressions involved in inflammation. Though the findings are promising, more research is needed to see how this translates to human health outcomes.
While evening primrose oil has traditionally been used for conditions like rheumatoid arthritis, the study highlighted that these LCFAs specifically target gene expressions involved in inflammation. Though the findings are promising, more research is needed to see how this translates to human health outcomes.
Read More
7
We examined the latest insights into herbal therapies for rheumatoid arthritis, including evening primrose oil. Our analysis included 22 studies, revealing moderate evidence suggesting that gamma linolenic acid (GLA), found in evening primrose oil, may ease pain and disability related to RA.
However, while some benefits were noted, the evidence remains mixed and the risk of side effects should not be overlooked. More comprehensive studies are needed to firmly establish its effectiveness for RA treatment.
However, while some benefits were noted, the evidence remains mixed and the risk of side effects should not be overlooked. More comprehensive studies are needed to firmly establish its effectiveness for RA treatment.
Read More
7
Evening primrose oil shows symptom relief
We explored the impact of evening primrose oil (EPO) on rheumatoid arthritis (RA) in a double-blind, placebo-controlled study involving 49 patients. Participants took EPO or EPO combined with fish oil, with the aim of reducing reliance on non-steroidal anti-inflammatory drugs (NSAIDs).
After 12 months, those on EPO noted significant improvements and were able to cut back on their NSAIDs. However, once they switched to placebo, they relapsed, revealing that while EPO may improve symptoms, it doesn't change the underlying disease. Thus, it appears evening primrose oil can help manage RA symptoms and lessen NSAID use, but it doesn’t modify the disease itself.
After 12 months, those on EPO noted significant improvements and were able to cut back on their NSAIDs. However, once they switched to placebo, they relapsed, revealing that while EPO may improve symptoms, it doesn't change the underlying disease. Thus, it appears evening primrose oil can help manage RA symptoms and lessen NSAID use, but it doesn’t modify the disease itself.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Boosts immunity
I combine evening primrose oil with B vitamins to enhance immunity for managing rheumatoid arthritis. This oil also improves skin turgor and benefits the overall condition of hair and nails. Regular use provides antimicrobial, regenerating, and anti-inflammatory effects.
Read More
7.5
Aids joint inflammation
Evening primrose oil aids in hormone restoration and has positive effects on women's health. While there’s no specific information regarding cholesterol, it does help regulate blood pressure. Importantly, it assists in treating rheumatoid arthritis. The oil is rich in omega-6 fatty polyunsaturated fatty acids, and a single small package lasts for a month of use.
Read More
7.5
Effective for acne
I have continuously taken evening primrose oil for several years, considering it the best female supplement for my skin. It has significantly helped with acne and has provided additional benefits, such as alleviating PMS pain and strengthening my nails. Most notably, it has proven benefits for rheumatoid arthritis and supports youthful skin.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Veselinovic M, Vasiljevic D, Vucic V, Arsic A, Petrovic S, et al. Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. Nutrients. 2017;9. doi:10.3390/nu9040325
- El-Sayed RM, Moustafa YM, El-Azab MF. Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1. Inflammopharmacology. 2014;22:305. doi:10.1007/s10787-014-0200-5
- Montserrat-de la Paz S, García-Giménez MD, Ángel-Martín M, Pérez-Camino MC, Fernández Arche A. Long-chain fatty alcohols from evening primrose oil inhibit the inflammatory response in murine peritoneal macrophages. J Ethnopharmacol. 2014;151:131. doi:10.1016/j.jep.2013.10.012
- Cameron M, Gagnier JJ, Chrubasik S. Herbal therapy for treating rheumatoid arthritis. Cochrane Database Syst Rev. 2011. doi:10.1002/14651858.CD002948.pub2
- Brzeski M, Madhok R, Capell HA. Evening primrose oil in patients with rheumatoid arthritis and side-effects of non-steroidal anti-inflammatory drugs. Br J Rheumatol. 1991;30:370.
- Belch JJ, Ansell D, Madhok R, O'Dowd A, Sturrock RD. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: a double blind placebo controlled study. Ann Rheum Dis. 1988;47:96.
